Fig 1: Positive rates of ADAM29 and FAM135B expression in various pathological grades of esophageal cancer. ADAM29, A Disintegrin And Metalloprotease Domain 29; FAM135B, Family with sequence similarity 135-member B; Normal, normal squamous epithelium; LGIN, low-grade intraepithelial neoplasia; HGIN, high-grade intraepithelial neoplasia; Cancer, esophageal squamous cell carcinoma. The expression levels of ADAM29 and FAM135B proteins were associated with the pathological grade.
Fig 2: ADAM29 and FAM135B protein expression using H&E staining, under microscope (magnification, ×400). (A) ADAM29 protein; and (B) FAM135B protein. (a) ESCC (brown); (b) esophageal high-grade intraepithelial neoplasia (yellow-brown); (c) esophageal low-grade intraepithelial neoplasia (yellow or light yellow); and (d) normal esophageal mucosal epithelium (light yellow or no coloring). ADAM29, a disintegrin and metalloprotease domain 29; FAM135B, family with sequence similarity 135-member B; H&E, hematoxylin and eosin; ESCC, esophageal squamous cell carcinoma.
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